| From US 412 W (Cimarron Turnpike from Tulsa) |
- Take Cimarron Turnpike spur (27 mile marker)take right fork. Continue for 6.9 miles.
- Take exit 21A for Perkins Rd. Exit to the right and turn left (south) on Perkins Rd.
- Continue for approximately 6 miles to 6th Ave. and turn right (west).
- Continue for approximately .4 miles to Main St.
- Turn left (south). St. James is located just south of the corner of 10th Ave. and S. Main St.

|
| From Interstate 35 |
- Take 174 exit for Stillwater
- Merge onto OK 51 East toward Stillwater (approximately 16 miles)
- Turn right at intersection of S. Main St.
- Continue to 1008 S. Main St.
|